(Albany, US) DelveInsight has launched a new report on ‘West Syndrome Market Insights, Epidemiology and Market Forecast– 2030’
DelveInsight’s ‘West Syndrome Market Insights, Epidemiology and Market Forecast– 2030’ report delivers an in-depth understanding of the West Syndrome, historical and forecasted epidemiology as well as the West Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some of West Syndrome Facts:
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Scope of West Syndrome Report:
West syndrome is an age-related specific epileptic encephalopathy due to multiple and diverse causes. It is characterized by a unique type of seizure called epileptic (infantile) spasms and gross EEG abnormalities of hypsarrhythmia. Usually, West syndrome consists of a characteristic triad: infantile spasms, the arrest of psychomotor development, and hypsarrhythmia, although one element may be missing.
West syndrome may be separated into two groups: the symptomatic group, which is characterized by previous existence of brain damage signs (psychomotor retardation, neurologic signs, radiologic signs, or other types of seizures) or by a known etiology, and the smaller, cryptogenic group that is characterized by a lack of previous signs of brain damage and known aetiology.
A specific cause for West Syndrome can be identified in approximately 70–75% of those affected. Any disorder that can lead to brain damage can be an underlying cause of West syndrome including trauma, brain malformations such as hemimegalencephaly or cortical dysplasia, infections, chromosomal abnormalities such as Down syndrome, neurocutaneous disorders such as tuberous sclerosis complex (TSC), Sturge Weber syndrome, incontinentia pigmenti (Bloch-Sulzberger syndrome), different metabolic/genetic diseases such as pyridoxine deficiency, nonketotic hyperglycemia, maple syrup urine disorder, phenylketonuria, mitochondrial encephalopathies and biotinidase deficiency, Otahara’s syndrome, and an abnormality (mutation) in the ARX gene or CDKL5 gene located on the X chromosome.
The spasms are linked to mental delays. The most common type of infantile spasms is the stiffening of the body. During the seizure, the child often has arms being thrown outward away from the body, the knees curled towards the body, upper body bending towards the knees. Sometimes other types of postures can also be seen but in rare cases such as legs and arms stiffened straight out from the body and head being thrown back.
The most common disorder responsible for West syndrome is tuberous sclerosis complex (TSC). TSC is an autosomal dominant genetic condition associated with seizures, eye, heart and kidney tumors and skin findings while X-linked West syndrome can be caused by a mutation in the CDKL5 gene or the ARX gene in the X chromosome. X-linked genetic disorders are conditions caused by a nonworking gene on the X chromosome and manifest mostly in males. While, females remain carrier to the condition.
Some of West Syndrome Companies:
West Syndrome Drugs Covered:
Table of Contents:
1 Key Insights
2 West Syndrome Market Overview at a Glance
3 Executive Summary of West Syndrome
4 West Syndrome: Disease Background and Overview
5 Diagnostic Algorithm for West Syndrome
6 Clinical Algorithm for Epileptic Spasms (Infantile Spasms) By Texas Children’s Hospital
7 Epidemiology and Patient Population
8 Country Wise-Epidemiology of West Syndrome
9 Treatment
10 Treatment Algorithm for West Syndrome
11 Guidelines for the Management and Treatment of Infantile Seizures
12 Recognized Establishments
13 Unmet Needs
14 Marketed Profiles
15 Emerging Drugs
16 West Syndrome: 7 Major Market Analysis
17 The United States Market Outlook
18 EU-5 Countries: Market Outlook
19 Japan Market Outlook
20 Case Reports
21 Market Drivers
22 Market Barriers
23 SWOT Analysis of West Syndrome
24 Appendix
25 DelveInsight Capabilities
26 Disclaimer
27 About DelveInsight
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